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Chromenes and coumarins from the roots of Paramignya trimera

Duong Hoang Trinh 1, *
Phuong Thu Tran 1
Hoa Dieu Lien Nguyen 1
Ly Dieu Ha 2
  1. University of Science, VNU-HCM
  2. School of Medicine, VNU-HCM
Correspondence to: Duong Hoang Trinh, University of Science, VNU-HCM. Email: pvphuc@vnuhcm.edu.vn.
Volume & Issue: Vol. 1 No. T5 (2017) | Page No.: 131-136 | DOI: 10.32508/stdjns.v1iT5.545
Published: 2018-11-29

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This article is published with open access by Viet Nam National University Ho Chi Minh City, Viet Nam. This article is distributed under the terms of the Creative Commons Attribution License (CC-BY 4.0) which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.

Abstract

Paramignya trimera, which belongs to the family Rutaceae, is used for the treatment of liver inflammation and cancer. Previous studies revealed that the roots of the species contained alkaloids, coumarins and chromenes. In this study, we reported the isolation of seven compounds from the roots collected in Phu Yen Province, comprising three chromenes, 2,2-dimethylchrom-3-en-6- carboxaldehyde (1), eulatachromene (2) and ninhvanin (3), together with four coumarins, 7- demethylsuberosin (4), xanthyletin (5), 6,7- dihydroxycoumarin (6) and 6-methoxy-7- hydroxycoumarin (7). Their chemical structures were elucidated using NMR techniques.

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